Liuba Orfenova made her debut in Western Europe at the Bregenzer Festspiele and worked as pianist / conductor's musical assistant and language coach at Paris Bastille (Boris Godounov, War and Peace, Khovanshchina), Bregenzer Festspiele (Mazeppa), Glyndebourne (The Queen of Spades, The Miserly Knight, The Duenna), Glyndebourne Touring (Eugene Onegin), Brussels La Monnaie (Khovanshchina, Lady Macbeth of Mtsensk, Eugene Onegin, The Queen of Spades, Boris Godounov, The Fiery Angel),  Dublin (Eugene Onegin), Toulouse (Boris Godounov), Ireland (Lady Macbeth of Mtsensk), Welsh National Opera (The Queen of Spades), Cardiff (Die Entführung aus dem Serail), Bologna (May Night, The Queen of Spades), Bordeaux (Eugene Onegin), Oslo (The Queen of Spades), Covent Garden (Lady Macbeth of Mtsensk), Liceu Barcelona (Lady Macbeth of Mtsensk, Boris Godounov, Khovanshchina), Frankfort (The Queen of Spades, Tsar's Bride), De Nederlandse Opera Amsterdam (Lady Macbeth of Mtsensk), among others.

She has worked for Teatro Real Madrid (Boris Godounov), Vlaamse Opera Antwerp (The Queen of Spades and Mazeppa), Operan Göteborg and Festival Glyndebourne (Eugene Onegin), De Nederlandse Opera Amsterdam (Boris Godounov), and Paris Bastille (Lady Macbeth of Mtsensk).

More recently Liuba Orfenova worked at ROH Covent Garden (Tchaikovsky's Cherevichki) and Lille (Eugene Onegin).

Upcoming engagements include Barcelona (The Queen of Spades), Semperoper Dresden (Iolanta), Amsterdam (Eugene Onegin and The Legend of the Invisible City of Kitezh), Madrid (Lady Macbeth of Mtsensk), and Paris Bastille (The Legend of the Invisible City of Kitezh).